Anti-D-Dimer antibody *Mouse anti-human, monoclonal IgG1*
Ordering information
| Price | |
| Catalog Number | |
| Unit Size | |
| Quantity |
Additional ordering information
| Telephone | 1-800-990-8053 |
| Fax | 1-800-609-2943 |
| sales@aatbio.com | |
| Quotation | Request |
| International | See distributors |
| Shipping | Standard overnight for United States, inquire for international |
Physical properties
| Solvent | Water |
Storage, safety and handling
| Intended use | Research Use Only (RUO) |
| Storage | Freeze (< -15 °C) |
| Overview |  SDSProtocol |
See also: Antibodies and Proteomics
Other names | Host mouse | Reactivity human | Application ELISA; LFIA; LETIA |
D-dimer is a small protein fragment, or fibrin degradation product (FDP), present in blood after a blood clot has been degraded by fibrinolysis. It is composed of two D fragments of the fibrin protein joined together by a cross-link. Elevated d-dimer levels are a key indicator or thrombotic events, indicating excess fibrinolysis, following activation of coagulation. In clinical biology, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation. Anti-D-Dimer monoclonal antibodies are highly sensitive for the detection of human D-dimer immunogens. They can be used in a broad range of immunoassays such as lateral-flow immunoassays (LFIA) and in IVD assay development.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of Anti-D-Dimer antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
| AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
| Proteins | HRP, Alkaline Phosphatase, Streptavidin |
| Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
| Small Molecules | Biotin |
| Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
| iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
| mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Images
Figure 1. Comparison between D-Dimer LFIA and diagnostic kit: 50 samples from donors were quantitatively tested using AAT Bioquest’s anti-D-Dimer antibodies in LFIA for the detection of D-dimer and a comparison kit. Results showed good correlation between both immunoassays, and the sensitivity reached to 0.2μg/ml.
Figure 2. Calibration curve for D-Dimer: human D-Dimer was reacted with anti-human D-Dimer antibody-coated latex, resulting in agglutination and increase in turbidity. Changes in turbidity were monitored with a spectrometer to quantitatively measure the D-Dimer concentration in the sample. The linear range is about 30μg/ml.
Figure 3. Comparison between D-Dimer LETIA and diagnostic kit: samples from donors（n=51) were detected using AAT Bioquest’s anti-D-Dimer antibodies in LETIA and a diagnostic kit. Results showed good correlation between both assays, and the sensitivity reached to 0.2μg/ml.