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Anti-Insulin-like growth factor-binding protein 1(IGFBP1) antibody
Mouse anti-human, monoclonal IgG1
Insulin-like growth factor-binding protein-1 (IGFBP-1), or placental protein 12 (PP12), belongs to a superfamily of IGFBPs that serve as carrier proteins for insulin-like growth factor (IGF-1). IGFBP-1 is synthesized and secreted by liver cells and by decidualized endometrial cells during pregnancy. It is expressed in liver, kidneys, and in amniotic fluid it is the most abundant IGFBP. IGFBP-1 binds equally to IGF-1 and IGF-II, and when phosphorylated IGFBP-1 exhibits higher binding affinities. In clinical biology, IGFBP-1 is a highly sensitive biomarker for the early diagnosis of premature rupture of fetal membranes (PROM) as the concentration of IGFBP-1 in amniotic fluid is 100 to 1000-fold higher than in human blood. Anti-IGFBP-1 monoclonal antibodies are highly sensitive for the detection of IGFBP-1 immunogens. They can be used for a broad range of immunoassays such as gold immunochromatography assays (GICA).
General packaging for catalogs V100171 and V100170. Actual shipped packaging may vary.
General packaging for catalogs V100171 and V100170. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
V10017050 ug
Price
V1001711 mg
Price
 
Antibody properties

Hostmouse
Reactivityhuman
ApplicationLFIA
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on October 12, 2025