Anti-Interleukin-6 (IL6) antibody *Mouse anti-human, monoclonal IgG1*

Anti-Interleukin-6 (IL6) antibody

Mouse anti-human, monoclonal IgG1

Interleukin 6 (IL-6) is a pleotropic cytokine encoded by the IL6 gene in humans. It acts as both a pro-inflammatory cytokine and as an anti-inflammatory myokine. IL-6 is essential for stimulating acute phase protein synthesis, hybridoma growth, bone metabolism, inflammation and cancer progression. In almost all diseases involving chronic inflammation, such as diabetes rheumatoid arthritis and congestive heart failure, the concentration of IL-6 is elevated. Anti-IL-6 monoclonal antibodies are highly specific for the detection of human IL-6. They can be used for a broad range of immunoassays such as chemiluminescent immunoassays (CLIA) and rapid sandwich immunoassays.

<p>Comparison of IL-6 CLIA and commercial diagnostic assays: 23 samples from healthy donors and patients with chronic infections were detected using MAb combination B (Cat# V100135 (Clone 2) - Cat# V100135 (Clone 4)) in CLIA IL-6 assay and a commercial diagnostic assay. The correlation coefficient between CLIA IL-6 assay and comparison assay is over 0.97. Results show that these monoclonal antibodies can be applied to double-MAb-sandwich-immunoassays.</p>

Protocol

COA

Catalog	Size	Price	Quantity
V100135	50 ug	Price
V100136	1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of Anti-Interleukin-6 (IL6) antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Host	mouse
Reactivity	human
Application	ELISA; CLIA; LFIA

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on October 11, 2025