Anti-Myeloperoxidase (MPO) antibody *Mouse anti-human, monoclonal IgG2b*

Anti-Myeloperoxidase (MPO) antibody

Mouse anti-human, monoclonal IgG2b

Myeloperoxidase (MPO) is a 150 kDa cationic hemoprotein that consists of two covalently bound subunits each containing a heavy chain (60 kDa) and a light chain (15 kDa). MPO is abundantly expressed in neutrophils and is released during degranulation. It plays a vital role in inflammatory responses by catalyzing chloride ion oxidation to produce hypochlorous acid which is used by neutrophils to kill bacteria and other pathogens. MPO is also known to cause oxidative modification of low density lipoproteins to a high uptake form. This is considered to be a key event in the promotion of atherogenesis and is linked to the progression of cardiovascular diseases. As such, MPO is considered to be a promising cardiovascular biomarker as elevated MPO levels indicates a high risk for atherosclerosis and coronary heart disease (CHD). Anti-MPO monoclonal antibodies are highly sensitive for the detection of human MPO. They can be used for a broad range of immunoassays such as latex enhanced turbidimetric immunoassays (LETIA), chemiluminescent immunoassays (CLIA) and ELISA.

<p>Samples from healthy donors and patients with myocardial injury were detected using the chemiluminescence immunoassay (CLIA) MPO assays, A and B. Results show good correlation between CLIA MPO assays and comparison kits.</p>

Protocol

COA

Catalog	Size	Price	Quantity
V100095	50 ug	Price
V100096	1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of Anti-Myeloperoxidase (MPO) antibody *Mouse anti-human, monoclonal IgG2b* with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Host	mouse
Reactivity	human
Application	LETIA; ELISA; CLIA; LFIA

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on October 5, 2025