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Anti-Neutrophil gelatinase-associated lipocalin (NGAL) antibody
Mouse anti-human, monoclonal IgG2b
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein expressed mostly in neutrophils. It is also present in lower levels in the kidney, prostate and epithelia of the respiratory and alimentary tracts. NGAL is a vital component in the innate immune response to bacterial infection. It limits bacterial growth by sequestering iron-containing microorganisms. NGAL's small size and protease resistant properties makes it easily excreted and detected in the urine. Under normal conditions, NGAL levels in the urine and plasma are low. However, in response to kidney injury NGAL levels increase sharply reaching diagnostic levels quickly. In clinical biology, NGAL is a novel biomarker of acute kidney injury (AKI) and is used in the early diagnosis of chronic kidney disease. Anti-NGAL monoclonal antibodies are highly sensitive for the detection of human NGAL. They can be used for a broad range of immunoassays such as chemiluminescent immunoassays (CLIA), latex enhanced turbidimetric immunoassays (LETIA), lateral-flow immunoassays (LFIA) and ELISA.
<p>Evaluation of the relative titers of four anti-NGAL MAbs stored at different temperature. AAT Bioquest&rsquo;s anti-human NGAL monoclonal antibodies presented in PBS buffer (without any preservative)&nbsp;were stored at -20&deg;C, 2-8&deg;C and 37&deg;C for&nbsp;15 days. During this period, the titers of four MAbs were determined in 3 day intervals.</p>
<p>Evaluation of the relative titers of four anti-NGAL MAbs stored at different temperature. AAT Bioquest&rsquo;s anti-human NGAL monoclonal antibodies presented in PBS buffer (without any preservative)&nbsp;were stored at -20&deg;C, 2-8&deg;C and 37&deg;C for&nbsp;15 days. During this period, the titers of four MAbs were determined in 3 day intervals.</p>
CatalogSize
Price
Quantity
V10000050 ug
Price
V1000011 mg
Price
 
Antibody properties

Hostmouse
Reactivityhuman
ApplicationELISA; CLIA; LFIA
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on October 13, 2025