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Anti-Serum amyloid A protein antibody
Mouse anti-human, monoclonal IgG2b
Serum amyloid A1 (SAA1) is a major acute-phase protein. It is produced primarily by hepatocytes in response to proinflammatory cytokines such as tumor necrosis factor α (TNF-α) or interleukin 6 (IL-6). Under inflammatory conditions, such as infection or malignancy, plasma concentrations of SAA1 can increase as high as 1000-fold. As such, it has become a promising reliable clinical indicator and biomarker for inflammatory diseases, chronic disorder and late-stage malignancy. Anti-SAA1 monoclonal antibodies are highly sensitive for the detection of human serum amyloid A1 immunogens. They can be used in the development of a broad range of immunoassays including gold immunochromatographic assays (GICA) and latex enhanced turbidimetric immunoassays (LETIA).
<p>Clinical comparison of AAT Bioquest&rsquo;s LETIA immunoassay and a competitor&rsquo;s immunoassay: anti-SAA1 monoclonal antibodies were evaluated in medium-scale clinical tries with 100 blood samples from donors. The correlation coefficient (r) is as high as 0.93 between in-house latex reagents and commercial SAA1 immunoassay showing good agreement between the two systems.</p>
<p>Clinical comparison of AAT Bioquest&rsquo;s LETIA immunoassay and a competitor&rsquo;s immunoassay: anti-SAA1 monoclonal antibodies were evaluated in medium-scale clinical tries with 100 blood samples from donors. The correlation coefficient (r) is as high as 0.93 between in-house latex reagents and commercial SAA1 immunoassay showing good agreement between the two systems.</p>
CatalogSize
Price
Quantity
V10014050 ug
Price
V1001411 mg
Price
 
Antibody properties

Hostmouse
Reactivityhuman
ApplicationLFIA; LETIA
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on October 13, 2025