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Anti-Thyroglobulin antibody
Mouse anti-human, monoclonal IgG1
Thyroglobulin (TG) is a 660 kDa glycoprotein homodimer produced by follicular cells of the thyroid gland. It is used predominately within the thyroid gland as a precursor for the synthesis of thyroxine and triiodothyronine, both of which are thyroid hormones essential for regulating metabolism. Under normal physiological conditions, the levels of thyroglobulin circulating in the blood stream are low. However, in any thyroid pathology the level of thyroglobulin increases making it a promising biomarker for thyroid cancers and thyroid diseases such as Graves' disease. Anti-TG monoclonal antibodies are highly sensitive for the detection of human thyroglobulin immunogens. They can be used for a broad range of immunoassays such as chemiluminescent immunoassays (CLIA), and for IVD assay development.
<p>Comparison between AAT Bioquest&rsquo;s CLIA TG immunoassay and a competitor&rsquo;s immunoassay: samples from donors were detected using different MAb combinations (A and B) from AAT Bioquest on a CLIA TG immunoassay, and compared to a competitor&rsquo;s immunoassay. Results showed good correlation between both systems. The MAb combinations used are (capture-detection): Mab combination A: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 2); and Mab combination B: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 3).</p>
<p>Comparison between AAT Bioquest&rsquo;s CLIA TG immunoassay and a competitor&rsquo;s immunoassay: samples from donors were detected using different MAb combinations (A and B) from AAT Bioquest on a CLIA TG immunoassay, and compared to a competitor&rsquo;s immunoassay. Results showed good correlation between both systems. The MAb combinations used are (capture-detection): Mab combination A: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 2); and Mab combination B: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 3).</p>
CatalogSize
Price
Quantity
V10015550 ug
Price
V1001561 mg
Price
 
Antibody properties

Hostmouse
Reactivityhuman
ApplicationELISA; CLIA
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on October 13, 2025