APC Anti-human CD158d Antibody *mAb#33*

The mAb#33 monoclonal antibody binds to human CD158d, a 45 - 50 kD transmembrane glycoprotein frequently expressed on the surface of natural killer cells. In certain organisms, CD158d negatively regulates natural killer cell mediated cytotoxicity, is an enhancer of cellular senescence and positively regulates natural killer cell cytokine production. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like HLA-Bw4. CD158d is a relatively rare antibody target, with fewer than 200 publications in the last decade. Even still, CD158d has been widely used in immunology and innate immunity research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 702/87 nm bandpass filter (for example, as in the Luminex Amnis CellStream).