APC Anti-human CD2 Antibody *AHC0031*

AHC0031 is an anti-human monoclonal antibody that recognizes the CD2 antigen. CD2 (also known as T11, SRBC or LFA-3 receptor) is a 45 kD single-pass type I membrane protein that is found on the surface of cells like NK cells and T cells. CD2 has been closely linked to vital biological processes like cell-cell adhesion, especially heterotypic cell-cell adhesion. Also, in certain organisms, it promotes interleukin-8 secretion, plays a role in the upregulation of myeloid dendritic cell activation and is an enhancer of tumor necrosis factor production. CD2 is a member of critical cellular pathways, namely, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like CD58. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is essential for costimulatory molecules and immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).

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