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APC Anti-human CD2 Antibody
HIT11
HIT11 is an anti-human monoclonal antibody that recognizes the CD2 antigen. CD2 (sometimes referred to as LFA-2) is a 45 kD single-pass type I membrane protein that is found on the surface of cells like T cells. CD2 has been thought to be involved with key biological processes such as cell-cell adhesion, especially heterotypic cell-cell adhesion. Also, in some organisms, it enhances myeloid dendritic cell activation, acts to positively regulate interferon-gamma secretion and is an enhancer of tumor necrosis factor production. CD2 is involved with key cellular pathways, for instance, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as LFA-3, CD59, CD58 and CD48. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 664/20 nm bandpass filter (for example, as in the Luminex Guava easyCyte).
Spectral emission profiles generated using four spatially offset lasers (355 nm, 405 nm, 488 nm, and 640 nm). Each laser produced a distinct emission pattern, and their combination yielded the composite spectral signature. (Bottom) Flow cytometry analysis of whole blood stained with APC Anti-human CD2 Antibody *HIT11*. The fluorescence signal was monitored using an Cytek Aurora flow cytometer in the specific R1-A channel.
Spectral emission profiles generated using four spatially offset lasers (355 nm, 405 nm, 488 nm, and 640 nm). Each laser produced a distinct emission pattern, and their combination yielded the composite spectral signature. (Bottom) Flow cytometry analysis of whole blood stained with APC Anti-human CD2 Antibody *HIT11*. The fluorescence signal was monitored using an Cytek Aurora flow cytometer in the specific R1-A channel.
CatalogSize
Price
Quantity
100201C025 tests
Price
100201C1100 tests
Price
100201C2500 tests
Price
 
Antibody properties

Other namesLFA-2, Erythrocyte R, T11
CloneHIT11
HostMouse
IsotypeIgG1
ReactivityHuman
Spectral properties

Correction factor (280 nm)0.195
Extinction coefficient (cm -1 M -1)
730000
Excitation (nm)651
Emission (nm)660
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on May 2, 2026