APC Anti-human CD25 Antibody *7G7B6*

The 7G7B6 monoclonal antibody recognizes human CD25, a 55 kD glycoprotein often located on the surface of oligodendrocytes, T cells, B cells and thymocytes. In certain organisms, CD25 negatively regulates defense response to virus, downregulates inflammatory response and positively regulates activated T cell proliferation. Additionally, it is involved with critical cellular pathways, for instance, the interleukin-2-mediated signaling pathway, cell surface receptor signaling pathway and cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like IL-2. CD25 is a very popular antibody target, with over 40000 publications in the last decade. CD25 is vital to immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 664/20 nm bandpass filter (for example, as in the Luminex Guava easyCyte).

Page updated on September 1, 2025