APC Anti-human/monkey CD154 Antibody *5C8*

5C8 is an anti-human/monkey monoclonal antibody that forms an immune complex with the CD154 antigen. CD154 (also known as gp39) is a 32 - 39 kD member of the TNF superfamily that is expressed on the surface of cells such as T cells. CD154 is associated with a variety of biologically interesting macromolecules/ligands, for instance, CD40. CD154 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD154 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).