Name: APC Anti-non-human primates/ human CD49b Antibody *AK7*
Brand: AAT Bioquest
SKU: 104911C0
Availability: InStock

APC Anti-non-human primates/ human CD49b Antibody

AK7

The AK7 monoclonal antibody reacts with non-human primates/ human CD49b, a 170 kD member of the Integrin alpha chain family commonly located on the surface of activated T cells, B cells and monocytes. In some organisms, CD49b plays a role in the upregulation of alkaline phosphatase activity, is involved in the positive regulation of translation and is a promoter of epithelial cell migration. Additionally, it plays a role in essential cellular pathways, for example, the integrin-mediated signaling pathway and collagen-activated signaling pathway. CD49b has been associated with critical biological processes such as cell adhesion, specifically cell adhesion mediated by integrin, and is associated with a variety of biologically interesting macromolecules/ligands, for example, laminin, collagen and MMP-1. CD49b is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD49b is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 664/20 nm bandpass filter (for example, as in the Luminex Guava easyCyte).

Datasheet

COA

Catalog	Size	Price
104911C0	25 tests	Price
104911C1	100 tests	Price
104911C2	500 tests	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of CD49b antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Other names	Integrin alpha-2, VLA-2 subunit alpha, ITGA2, α2 integrin, VLA-2 α chain, Integrin α2 chain
Clone	AK7
Host	Mouse
Isotype	IgG1
Reactivity	Non-Human Primates, Human

Spectral properties

Correction factor (280 nm)	0.195
Extinction coefficient (cm ^-1 M ^-1)	730000
Excitation (nm)	651
Emission (nm)	660

Usage and storage

Intended use

Research Use Only (RUO)

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Page updated on July 26, 2026