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APC/Cy7 Anti-human CD3 Antibody
UCHT1
The UCHT1 monoclonal antibody binds to human CD3e, a 20 kD member of the Ig superfamily commonly found on the surface of tregs, thymocytes, nkt cells and thymocytes (differentiation dependent)s. In many organisms, CD3 enhances interleukin-4 production, is an inhibitor of gene expression and negatively regulates smoothened signaling pathway. Also, it plays a role in essential cellular pathways, for instance, the cell surface receptor signaling pathway, T cell receptor signaling pathway and apoptotic signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like TCR. CD3 is a very popular antibody target, with over 80000 publications in the last decade. CD3e is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to APC/Cy7 (ex/em = 754/779 nm).
(Top) Spectral emission profiles generated using four spatially offset lasers (355 nm, 405 nm, 488 nm, and 640 nm). Each laser produced a distinct emission pattern, and their combination yielded the composite spectral signature. (Bottom) Flow cytometry analysis of whole blood stained with APC/Cy7 Anti-human CD3 Antibody *UCHT1*. The fluorescence signal was monitored using an Cytek Aurora flow cytometer in the specific R7-A channel.
(Top) Spectral emission profiles generated using four spatially offset lasers (355 nm, 405 nm, 488 nm, and 640 nm). Each laser produced a distinct emission pattern, and their combination yielded the composite spectral signature. (Bottom) Flow cytometry analysis of whole blood stained with APC/Cy7 Anti-human CD3 Antibody *UCHT1*. The fluorescence signal was monitored using an Cytek Aurora flow cytometer in the specific R7-A channel.
datasheet
Datasheet
sds
SDS
COA
CatalogSize
Price
Quantity
100321D025 tests
Price
100321D1100 tests
Price
100321D2500 tests
Price
 
Antibody properties
Other namesT3E
CloneUCHT1
HostMouse
ReactivityHuman
Spectral properties
Extinction coefficient (cm -1 M -1)
700000
Excitation (nm)651
Emission (nm)779
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 3, 2026