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AAT Bioquest

APC/Cy7 Anti-human CD41 Antibody *HIP2*

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Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Spectral properties
Extinction coefficient (cm -1 M -1)700000
Excitation (nm)651
Emission (nm)779
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

OverviewpdfSDSpdfProtocol


Other names
GPIIb; ITGA2B
Clone
HIP2
Host
mouse
Isotype
mouse IgG3
Reactivity
human
Application
Extinction coefficient (cm -1 M -1)
700000
Excitation (nm)
651
Emission (nm)
779
The HIP2 monoclonal antibody binds to human CD41, a 22 kD glycoprotein frequently expressed on the surface of megakaryocytes and platelets. In certain organisms, CD41 is a promoter of leukocyte migration. Also, it acts in important cellular pathways, for example, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as von Willebrand factor (vWF), Fibrinogen and Fibronectin. CD41 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD41 is vital to cell adhesion, immunology and cell biology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC/Cy7 (ex/em = 754/779 nm).

Spectrum


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spectrum

Spectral properties

Extinction coefficient (cm -1 M -1)700000
Excitation (nm)651
Emission (nm)779

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Conjugation


We provide custom conjugation services for this antibody (eg. labeling of cd41 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.