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APC/Cy7 Anti-human CD47 Antibody
B6.H12
B6.H12 is an anti-human monoclonal antibody that is specific for the CD47 antigen. CD47 (sometimes called MER6, Integrin associated protein or integrin-associated protein) is a 42 - 52 kD multi-pass membrane protein that is located on the surface of cells like T cells, erythrocytes, epithelial cells and endothelial cells. CD47 acts in essential cellular pathways, for instance, the negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis and integrin-mediated signaling pathway. Also, in some organisms, it is involved in the positive regulation of stress fiber assembly, is a promoter of T cell activation and positively regulates phagocytosis. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like CD61. CD47 is a fairly uncommon antibody target, with a little more than 5000 publications in the last decade. Even still, CD47 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to APC/Cy7 (ex/em = 754/779 nm).
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CatalogSize
Price
Quantity
104721D025 tests
Price
104721D1100 tests
Price
104721D2500 tests
Price
 
Antibody properties

Other namesgp42, IAP, neurophilin, MER6, Integrin associated protein
CloneB6.H12
HostMouse
IsotypeIgG1, kappa
ReactivityHuman
Spectral properties

Extinction coefficient (cm -1 M -1)
700000
Excitation (nm)651
Emission (nm)779
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 20, 2026