APC/XFD750 Anti-human CD147 Antibody *MEM-M6/6*

The MEM-M6/6 monoclonal antibody binds to human CD147, a 55 - 65 kD member of the Ig superfamily often expressed on the surface of endothelial cells and leukocytes. In certain organisms, CD147 acts to positively regulate interleukin-6 production. Moreover, it is a component of key cellular pathways, for example, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands. CD147 is a fairly uncommon antibody target, with a little more than 3200 publications in the last decade. Even still, CD147 has been widely used in cell adhesion and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC/XFD750 (ex/em = 756/785 nm). XFD750 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 750 (Alexa Fluor® is the trademark of Thermo Fisher).

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