Name: APC/XFD750 Anti-human CD300a Antibody *MEM-260*
Brand: AAT Bioquest
SKU: 130001D0
Availability: InStock

APC/XFD750 Anti-human CD300a Antibody

MEM-260

MEM-260 is an anti-human monoclonal antibody that is specific for the CD300a antigen. CD300a (alternatively called CLM-8) is a transmembrane protein that is expressed on the surface of cells such as macrophages, T cells, dendritic cells and B cells. In some organisms, CD300a is a repressor of MyD88-dependent toll-like receptor signaling pathway, suppresses B cell receptor signaling pathway and is a promoter of phosphoprotein phosphatase activity. Also, it is a member of important cellular pathways, for example, the negative regulation of B cell receptor signaling pathway, negative regulation of MyD88-dependent toll-like receptor signaling pathway and regulation of T cell receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like unknown. CD300a is a relatively rare antibody target, with fewer than 400 publications in the last decade. Even still, CD300a is essential for innate immunity and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC/XFD750 (ex/em = 756/785 nm). XFD750 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 750 (Alexa Fluor® is the trademark of Thermo Fisher).

Datasheet

COA

Catalog	Size	Price
130001D0	25 tests	Price
130001D1	100 tests	Price
130001D2	500 tests	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of CD300a antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Other names	CLM-8, IRp60, CMRF-35H
Clone	MEM-260
Host	Mouse
Isotype	IgG1
Reactivity	Human

Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	700000
Excitation (nm)	651
Emission (nm)	785

Usage and storage

Intended use

Research Use Only (RUO)

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Page updated on August 21, 2026