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Biotin-cAMP conjugate

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Physical properties
Molecular weight988.11
Storage, safety and handling
Intended useResearch Use Only (RUO)
StorageFreeze (< -15 °C); Minimize light exposure
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Molecular weight
Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction. It is synthesized from adenosine triphosphate (ATP) by enzymes (g-proteins) that are attached to metabotropic receptors and become released when the receptor is activated. Cyclic AMP is involved in the regulation of glycogen, sugar, and lipid metabolism. This cAMP-biotin conjugate is an excellent probe that can be used for developing cAMP assays.


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Biotin-cAMP conjugate to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM101.203 µL506.017 µL1.012 mL5.06 mL10.12 mL
5 mM20.241 µL101.203 µL202.407 µL1.012 mL2.024 mL
10 mM10.12 µL50.602 µL101.203 µL506.017 µL1.012 mL

Molarity calculator

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Mass (Calculate)Molecular weightVolume (Calculate)Concentration (Calculate)Moles



View all 60 citations: Citation Explorer
cAMP and c-di-GMP synergistically support biofilm maintenance through the direct interaction of their effectors
Authors: Liu, Cong and Sun, Di and Liu, Jiawen and Chen, Ying and Zhou, Xuge and Ru, Yunrui and Zhu, Jingrong and Liu, Weijie
Journal: Nature communications (2022): 1--15
Roles of Cyclic AMP Response Element Binding Activation in the ERK1/2 and p38 MAPK Signalling Pathway in Central Nervous System, Cardiovascular System, Osteoclast Differentiation and Mucin and Cytokine Production
Authors: Koga, Y., Tsurumaki, H., Aoki-Saito, H., Sato, M., Yatomi, M., Takehara, K., Hisada, T.
Journal: Int J Mol Sci (2019): ersion="1.0" encoding="UTF-8" ?>17102.enlEndN
Making and Breaking of an Essential Poison: the Cyclases and Phosphodiesterases That Produce and Degrade the Essential Second Messenger Cyclic di-AMP in Bacteria
Authors: Commichau, F. M., Heidemann, J. L., Ficner, R., Stulke, J.
Journal: J Bacteriol (2019): se name="17102.enl" path="C:\Users\aatbi\Drop
Cyclic di-AMP in host-pathogen interactions
Authors: Devaux, L., Kaminski, P. A., Trieu-Cuot, P., Firon, A.
Journal: Curr Opin Microbiol (2018): 21-28
Natural products as modulators of the cyclic-AMP pathway: evaluation and synthesis of lead compounds
Authors: Sengupta, S., Mehta, G.
Journal: Org Biomol Chem (2018): 6372-6390
Perspective of ions and messengers: an intricate link between potassium, glutamate, and cyclic di-AMP
Authors: Gundlach, J., Commichau, F. M., Stulke, J.
Journal: Curr Genet (2018): 191-195
The cyclic AMP phosphodiesterase 4D5 (PDE4D5)/receptor for activated C-kinase 1 (RACK1) signalling complex as a sensor of the extracellular nano-environment
Authors: Yarwood, S. J., Parnell, E., Bird, R. J.
Journal: Cell Signal (2017): 282-289
Interrogating cyclic AMP signaling using optical approaches
Authors: Jiang, J. Y., Falcone, J. L., Curci, S., Hofer, A. M.
Journal: Cell Calcium (2017): 47-56
Regulation of Cancer Cell Responsiveness to Ionizing Radiation Treatment by Cyclic AMP Response Element Binding Nuclear Transcription Factor
Authors: D&apos;Auria, F., Centurione, L., Centurione, M. A., Angelini, A., Di Pietro, R.
Journal: Front Oncol (2017): 76
Role of cyclic AMP in the eye with glaucoma
Authors: Shim, M. S., Kim, K. Y., Ju, W. K.
Journal: BMB Rep (2017): 60-70