Biotin-cAMP conjugate

Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction. It is synthesized from adenosine triphosphate (ATP) by enzymes (g-proteins) that are attached to metabotropic receptors and become released when the receptor is activated. Cyclic AMP is involved in the regulation of glycogen, sugar, and lipid metabolism. This cAMP-biotin conjugate is an excellent probe that can be used for developing cAMP assays.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
17105	100 ug	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Biotin-cAMP conjugate to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	101.203 µL	506.017 µL	1.012 mL	5.06 mL	10.12 mL
5 mM	20.241 µL	101.203 µL	202.407 µL	1.012 mL	2.024 mL
10 mM	10.12 µL	50.602 µL	101.203 µL	506.017 µL	1.012 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	988.11 g/mol	=	mL	x	mM	=	mmol

Citations

View all 61 citations: Citation Explorer

2′ 3′-cGAMP interactome identifies 2′ 3′-cGAMP/Rab18/FosB signaling in cell migration control independent of innate immunity

Authors:

Deng, Yu and Hahn, Quentin and Yu, Le and Zhu, Zhichuan and Boyer, Joshua A and Wang, Jian and Kong, Deyu and Carey, Leiah M and Hepperla, Austin J and Simon, Jeremy M and others,

Journal:

Science Advances (2024): eado7024

cAMP and c-di-GMP synergistically support biofilm maintenance through the direct interaction of their effectors

Authors:

Liu, Cong and Sun, Di and Liu, Jiawen and Chen, Ying and Zhou, Xuge and Ru, Yunrui and Zhu, Jingrong and Liu, Weijie

Journal:

Nature communications (2022): 1--15

Roles of Cyclic AMP Response Element Binding Activation in the ERK1/2 and p38 MAPK Signalling Pathway in Central Nervous System, Cardiovascular System, Osteoclast Differentiation and Mucin and Cytokine Production

Authors:

Koga, Y., Tsurumaki, H., Aoki-Saito, H., Sato, M., Yatomi, M., Takehara, K., Hisada, T.

Journal:

Int J Mol Sci (2019): ersion="1.0" encoding="UTF-8" ?>17102.enlEndN

Making and Breaking of an Essential Poison: the Cyclases and Phosphodiesterases That Produce and Degrade the Essential Second Messenger Cyclic di-AMP in Bacteria

Authors:

Commichau, F. M., Heidemann, J. L., Ficner, R., Stulke, J.

Journal:

J Bacteriol (2019): se name="17102.enl" path="C:\Users\aatbi\Drop

Cyclic di-AMP in host-pathogen interactions

Authors:

Devaux, L., Kaminski, P. A., Trieu-Cuot, P., Firon, A.

Journal:

Curr Opin Microbiol (2018): 21-28

Physical properties

Molecular weight	988.11
Solvent	DMSO

Storage, safety and handling

Intended use	Research Use Only (RUO)
Storage	Freeze (< -15 °C); Minimize light exposure

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on October 13, 2025