Biotin Mouse Anti-human β2-Microglobulin Antibody *B2M-01, monoclonal, Cross Adsorbed*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Overview | Protocol |
See also: Antibodies and Proteomics, Immunoprecipitation
Other names | Clone B2M-01 | Host mouse | Reactivity human | Application FC (QC TESTED); IP; WB; IHC(P); ICC; ELISA |
β-2-Microglobulin is a 16 kDa protein that can be located in the tertiary granule lumen, extracellular exosome and recycling endosome membrane of cells. Sequencing of β-2-microglobulin has shown it contains a primary structural unit, the Ig-like C1-type domain. β-2-Microglobulin recognizes identical protein. It downregulates epithelial cell proliferation, neurogenesis and neuron projection development. But on the other hand, it also positively regulates cellular senescence, transferrin receptor binding and T cell mediated cytotoxicity. β-2-Microglobulin has been found to be involved in organismal processes, for example, modulation of age-related behavioral decline, response to molecule of bacterial origin and cellular response to iron(III) ion. β-2-Microglobulin is the subject of extensive research because of the fact that it plays a role in the interferon-γ-mediated signaling pathway. β-2-microglobulin is clinically significant because abnormalities in its function have been associated with diseases like Amyloidosis 8 (AMYL8) and Immunodeficiency 43 (IMD43). Amyloidosis 8, an autosomal dominant inheritancedisorder characterized by proteinuria, hypertensive disorder and edema, has especially been of interest to researchers.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of β2-Microglobulin antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Application notes
A Meta-Analysis of Common Calcium Indicators
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Abbreviation of Common Chemical Compounds Related to Peptides
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Abbreviation of Common Chemical Compounds Related to Peptides
FAQ
Are Cell Navigator® Cell Plasma Membrane Staining Kits suitable for cell culture medium samples?
Are there any alternatives to BrdU (Bromodeoxyuridine)?
Are there any alternatives to Cy5?
Are there any alternatives to indocyanine green (ICG)?
Are there any calcium indicators that don't require probenecid (PBC)?
Are there any alternatives to BrdU (Bromodeoxyuridine)?
Are there any alternatives to Cy5?
Are there any alternatives to indocyanine green (ICG)?
Are there any calcium indicators that don't require probenecid (PBC)?