Biotin Mouse Anti-human Cytokeratin 18 Antibody *DA-7, monoclonal, Cross Adsorbed*
Ordering information
Price | |
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Overview | SDSProtocol |
See also: Antibodies and Proteomics, Immunoprecipitation
Other names | Clone DA-7 | Host mouse | Reactivity human | Application IP; WB; IHC(P); ICC; ELISA |
Keratin, type I cytoskeletal 18 is a 56 kDa protein that can be found in the nucleolus, cytoplasm and microtubule organizing center of cells. It is sometimes referred to as cell proliferation-inducing gene 46 protein, Keratin-18 or Cytokeratin-18. In Homo sapiens, keratin, type I cytoskeletal 18 recognizes scaffold protein, cadherin involved in cell-cell adhesion and RNA. It is an integral part of organismal processes, for example, intermediate filament cytoskeleton organization, anatomical structure morphogenesis and Golgi to plasma membrane CFTR protein transport. It is the subject of intensive study stemming from the fact that it is a member of the extrinsic apoptotic signaling pathway and tumor necrosis factor-mediated signaling pathway. Sequencing of Keratin, type I cytoskeletal 18 has shown evidence that it contains a primary structural unit, the IF rod domain. It has been closely linked to essential functions like structural molecule activity. Keratin, type I cytoskeletal 18 is a negative regulator of apoptotic process. Mutations and abnormalities in Keratin, type I cytoskeletal 18 have been associated with a number of diseases, for example, Cirrhosis (CIRRH).
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of Cytokeratin 18 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Application notes
A Meta-Analysis of Common Calcium Indicators
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Abbreviation of Common Chemical Compounds Related to Peptides
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Abbreviation of Common Chemical Compounds Related to Peptides
FAQ
Are Cell Navigator® Cell Plasma Membrane Staining Kits suitable for cell culture medium samples?
Are there any alternatives to BrdU (Bromodeoxyuridine)?
Are there any alternatives to Cy5?
Are there any alternatives to indocyanine green (ICG)?
Are there any calcium indicators that don't require probenecid (PBC)?
Are there any alternatives to BrdU (Bromodeoxyuridine)?
Are there any alternatives to Cy5?
Are there any alternatives to indocyanine green (ICG)?
Are there any calcium indicators that don't require probenecid (PBC)?