Name: DiBAC4(3) [Bis-(1,3-dibutylbarbituric acid)trimethine oxonol]
Brand: AAT Bioquest
SKU: 21411
Price: 115 USD
Availability: InStock

DiBAC4(3)

Bis-(1,3-dibutylbarbituric acid)trimethine oxonol

DiBAC4(3) is a sensitive slow-response probe for measuring cellular membrane potential. In general, slow-response probes exhibit potential-dependent changes in their transmembrane distribution that are accompanied by a fluorescence change. The magnitude of their optical responses is much larger than that of fast-response probes (typically a 1% fluorescence change per mV). Slow-response probes, which include cationic carbocyanines, rhodamines and anionic oxonols, are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.

Catalog	Size	Price	Quantity
21411	25 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of DiBAC4(3) [Bis-(1,3-dibutylbarbituric acid)trimethine oxonol] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	193.558 µL	967.792 µL	1.936 mL	9.678 mL	19.356 mL
5 mM	38.712 µL	193.558 µL	387.117 µL	1.936 mL	3.871 mL
10 mM	19.356 µL	96.779 µL	193.558 µL	967.792 µL	1.936 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	516.64 g/mol	=	mL	x	mM	=	mmol

Citations

View all 19 citations: Citation Explorer

Deciphering the metabolic details of L-lysine toxicity in cyanobacteria

Authors:

Enkerlin, Andreas M and Hoffmann, Uta A and Rapp, Johanna and Miao, Rui and Link, Hannes and Hudson, Elton P and Selim, Khaled A

Journal:

bioRxiv (2025): 2025--03

K2P2. 1 channels modulate the pH-and mechanosensitivity of pancreatic stellate cells

Authors:

Rugi, Micol and Hofschr{\"o}er, Verena and Peth{\H{o}}, Zolt{\'a}n and Soret, Benjamin and Loeck, Thorsten and Schwab, Albrecht

Journal:

Pfl{\"u}gers Archiv-European Journal of Physiology (2024): 1--11

Co-exposure to pentachlorophenol (PCP) and cadmium (Cd) triggers apoptosis-like cell death in Eschericia coli

Authors:

Chen, Zhilan and Jiang, Yi and Lai, Xuebin and Zhu, Chenhong and Zhang, Dapeng and Wang, Hailin

Journal:

Environmental Pollution (2024): 123640

Membrane Domain Anti-Registration Induces an Intrinsic Transmembrane Potential

Authors:

Lin, Xiaoqian and Lin, Kaidong and He, Shiqi and Zhou, Yue and Li, Xiu and Lin, Xubo

Journal:

Langmuir (2023)

Regulation of localized corrosion of 316L stainless steel on osteogenic differentiation of bone morrow derived mesenchymal stem cells

Authors:

Li, Meng and Wu, Jing and Geng, Wenbo and Yang, Yulu and Li, Xuan and Xu, Kun and Li, Ke and Li, Yan and Duan, Qiaojian and Gao, Pengfei and others,

Journal:

Biomaterials (2023): 122262

References

View all 36 references: Citation Explorer

Activation of Ca(2+)-activated potassium channels is involved in lysophosphatidylcholine-induced monocyte adhesion to endothelial cells

Authors:

Erdogan A, Schaefer MB, Kuhlmann CR, Most A, Hartmann M, Mayer K, Renner FC, Schaefer C, Abdallah Y, Hoelschermann H, Schaefer CA.

Journal:

Atherosclerosis. (2006)

The Zn2+-transporting pathways in pancreatic beta-cells: a role for the L-type voltage-gated Ca2+ channel

Authors:

Gyulkh, undefined and anyan AV, Lee SC, Bikopoulos G, Dai F, Wheeler MB.

Journal:

J Biol Chem (2006): 9361

N-terminal parathyroid hormone-related peptide hyperpolarizes endothelial cells and causes a reduction of the coronary resistance of the rat heart via endothelial hyperpolarization

Authors:

Abdallah Y, Ross G, Dolf A, Heinemann MP, Schluter KD.

Journal:

Peptides (2006): 2927

Rapid assessment of the physiological status of Streptococcus macedonicus by flow cytometry and fluorescence probes

Authors:

Papadimitriou K, Pratsinis H, Nebe-von-Caron G, Kletsas D, Tsakalidou E.

Journal:

Int J Food Microbiol (2006): 197

Role of cGMP in sildenafil-induced activation of endothelial Ca2+-activated K+ channels

Authors:

Luedders DW, Muenz BM, Li F, Rueckleben S, Tillmanns H, Waldecker B, Wiecha J, Erdogan A, Schaefer CA, Kuhlmann CR.

Journal:

J Cardiovasc Pharmacol (2006): 365

Physical properties

Molecular weight	516.64
Solvent	DMSO

Spectral properties

Excitation (nm)	493
Emission (nm)	517

Storage, safety and handling

Certificate of Origin	Download PDF
H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200
CAS	70363-83-6

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Page updated on September 25, 2025