FITC Anti-human CD1 Antibody *OKT-6*

OKT-6 is an anti-human monoclonal antibody that recognizes the CD1a antigen. CD1a (alternatively called T6 or R4) is a 49 kD member of the Ig superfamily that is found on the surface of cells like T cells, B cells, dendritic cells and macrophages. CD1 has been thought to be involved with key biological processes such as immune response, particularly adaptive immune response. Additionally, in some organisms, it acts to positively regulate T cell mediated cytotoxicity. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as β-2-Microglobulin and CD74. CD1 is a moderately popular antibody target, with over 15000 publications in the last decade. CD1a is vital to innate immunity and immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to FITC (ex/em = 491/516 nm). It is compatible with the 488 nm laser and 530/30 nm bandpass filter (for example, as in the BD LSRFortessa™ X-20).

Page updated on April 25, 2025