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FITC Anti-human CD117 Antibody
104D2
The 104D2 monoclonal antibody reacts with human CD117, a 145 kD single-pass type i membrane protein typically found on the surface of leukemias, embryonic stem cells, mesenchymal stem cells and mast cells. CD117 has been closely linked to vital biological processes like germ cell migration, specifically ectopic germ cell programmed cell death. In addition, in some organisms, it acts to positively regulate pseudopodium assembly, plays a role in the upregulation of long-term neuronal synaptic plasticity and is an inhibitor of programmed cell death. CD117 is a component of critical cellular pathways, for example, the transmembrane receptor protein tyrosine kinase signaling pathway, Kit signaling pathway and Fc receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as MGF, SCF and KL. CD117 is a moderately popular antibody target, with over 11000 publications in the last decade. CD117 has been widely used in stem cells and immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to FITC (ex/em = 491/516 nm). It is compatible with the 488 nm laser and 530/40 nm bandpass filter (for example, as in the BD FACSJazz™).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 111701H0 | 100 tests | Price | |
| 111701H1 | 500 tests | Price |
Antibody properties
| Other names | c-kit; SCFR |
| Clone | 104D2 |
| Host | mouse |
| Isotype | mouse IgG1 |
| Reactivity | human |
| Application | Flow Cytometry (FACS); Fluorescence Imaging |
Spectral properties
| Correction factor (280 nm) | 0.35 |
| Extinction coefficient (cm -1 M -1) | 73000 |
| Excitation (nm) | 491 |
| Emission (nm) | 516 |
| Quantum yield | 0.92 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on October 28, 2025