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FITC Anti-human CD31 Antibody
MEM-05
The MEM-05 monoclonal antibody reacts with human CD31, a 130 - 140 kD transmembrane glycoprotein commonly found on the surface of monocytes and endothelial cells. CD31 has been closely linked to key biological processes like cell-cell adhesion, particularly leukocyte cell-cell adhesion. In addition, in certain organisms, it is an enhancer of peptidyl-tyrosine phosphorylation, plays a role in the upregulation of cell migration and plays a role in the upregulation of protein localization to cell-cell junction. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as CD38. CD31 is a very popular antibody target, with over 32000 publications in the last decade. CD31 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of angiogenesis and immunology. This antibody was purified through affinity chromatography and conjugated to FITC (ex/em = 491/516 nm). It is compatible with the 488 nm laser and 525/45 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Advanteon).
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CatalogSize
Price
Quantity
103101I0100 tests
Price
103101I1500 tests
Price
 
Antibody properties

Other namesPECAM-1, EndoCAM, Platelet endothelial cell adhesion molecule
CloneMEM-05
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Absorbance (nm)488
Correction factor (280 nm)0.35
Extinction coefficient (cm -1 M -1)
73000
Excitation (nm)491
Emission (nm)516
Quantum yield
0.92
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on August 5, 2024