FITC Anti-human CD41 Antibody *HIP2*

The HIP2 monoclonal antibody binds to human CD41, a 22 kD glycoprotein frequently expressed on the surface of megakaryocytes and platelets. In certain organisms, CD41 is a promoter of leukocyte migration. Also, it acts in important cellular pathways, for example, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as von Willebrand factor (vWF), Fibrinogen and Fibronectin. CD41 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD41 is vital to cell adhesion, immunology and cell biology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to FITC (ex/em = 491/516 nm). It is compatible with the 488 nm laser and 512/18 nm bandpass filter (for example, as in the Luminex Guava easyCyte).

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