FITC Mouse Anti-human Myeloperoxidase Antibody *MPO421-8B2, monoclonal*

Myeloperoxidase (MPO) is a 84 kDa protein, located in the extracellular exosome, intracellular membrane-bounded organelle and nucleoplasm of cells. In Homo sapiens, myeloperoxidase suppresses apoptotic process, and moreover, recognizes heme, metal ion and chromatin. Myeloperoxidase is an integral part of organismal processes, in particular, removal of superoxide radicals, response to gold nanoparticle and response to lipopolysaccharide. It has been closely linked to critical functions like peroxidase activity. Mutations and abnormalities in myeloperoxidase have been closely linked to a number of diseases, in particular, myeloperoxidase deficiency (MPOD). Myeloperoxidase deficiency, an autosomal recessive inheritancedisorder characterized by abnormality of blood and blood-forming tissues, abnormality of metabolism/homeostasis and abnormality of the immune system, has in specific been of interest to investigators.