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iFluor® 405 Anti-human CD2 Antibody
RPA-2.10
RPA-2.10 is an anti-human monoclonal antibody that is specific for the CD2 antigen. CD2 (sometimes referred to as T11, Rosette receptor, Erythrocyte receptor or LFA-2) is a 45 kD single-pass type I membrane protein that is located on the surface of cells such as T cells, B cells and NK cells. In certain organisms, CD2 positively regulates interleukin-8 secretion, enhances myeloid dendritic cell activation and is an enhancer of interferon-gamma secretion. Also, it has been thought to be involved with important biological processes like cell-cell adhesion, specifically heterotypic cell-cell adhesion. CD2 is involved with key cellular pathways, in particular, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like CD48, LFA-3 and CD58. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules and immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 405 (ex/em = 403/427 nm). It is compatible with the 405 nm laser and 445/45 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Quanteon).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10021020 | 100 tests | Price | |
| 10021021 | 500 tests | Price |
Antibody properties
| Other names | LFA-2, Erythrocyte R, T11 |
| Clone | RPA-2.10 |
| Host | Mouse |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.48 |
| Correction factor (280 nm) | 0.77 |
| Extinction coefficient (cm -1 M -1) | 37000 1 |
| Excitation (nm) | 403 |
| Emission (nm) | 427 |
| Quantum yield | 0.91 1 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 1, 2026