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iFluor® 488 Anti-human CD24 Antibody
HI45
HI45 is an anti-human monoclonal antibody that is specific for the CD24 antigen. CD24 (also known as Nectadrin or Ly-52) is a 35 - 45 kD transmembrane protein that is expressed on the surface of cells such as granulocytes, B cells and epithelial cells. CD24 acts in important cellular pathways, for instance, the immune response-regulating cell surface receptor signaling pathway, Wnt signaling pathway and intrinsic apoptotic signaling pathway. Also, in some organisms, it is involved in the negative regulation of transforming growth factor beta3 production, plays a role in the upregulation of activated T cell proliferation and is involved in the positive regulation of MAP kinase activity. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like CD62P (P-Selectin). CD24 is a moderately popular antibody target, with over 12000 publications in the last decade. CD24 has a variety of applications in cell biology and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 488 (ex/em = 491/516 nm). It is compatible with the 488 nm laser and 525/50 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant Analyzer 10).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10240050 | 100 tests | Price | |
| 10240051 | 500 tests | Price |
Antibody properties
| Other names | Nectadrin; HSA |
| Clone | HI45 |
| Host | mouse |
| Isotype | mouse IgG1 |
| Reactivity | human |
| Application | Flow Cytometry (FACS); Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.21 |
| Correction factor (280 nm) | 0.11 |
| Extinction coefficient (cm -1 M -1) | 75000 1 |
| Excitation (nm) | 491 |
| Emission (nm) | 516 |
| Quantum yield | 0.9 1 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on November 8, 2025