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iFluor® 514 Anti-human CD10 Antibody
HI10a
HI10a is an anti-human monoclonal antibody that targets the CD10 antigen. CD10 (also known as EPN, MME, CALLA or Neprilysin) is a 100 kD single-pass type II membrane protein that is expressed on the surface of cells such as NK cells and endothelial cells. CD10 has been closely linked to essential biological processes like amyloid-beta clearance, particularly amyloid-beta clearance by cellular catabolic process. Also, in some organisms, it is involved in the positive regulation of long-term synaptic potentiation and is a promoter of neurogenesis. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like . CD10 is a fairly uncommon antibody target, with a little more than 9600 publications in the last decade. Even still, CD10 has been widely used in immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 514 (ex/em = 510/527 nm). It is compatible with the 532 nm laser and 575/25 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10100060 | 100 tests | Price | |
| 10100061 | 500 tests | Price |
Physical properties
| Molecular weight | N/A |
| Solvent | water |
Antibody properties
| Other names | CALLA, MME, Neprilysin |
| Clone | HI10a |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Absorbance (nm) | 511 |
| Correction factor (260 nm) | 0.265 |
| Correction factor (280 nm) | 0.116 |
| Extinction coefficient (cm -1 M -1) | 75000 1 |
| Excitation (nm) | 511 |
| Emission (nm) | 527 |
| Quantum yield | 0.83 1 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
| Storage | Refrigerated (2-8 °C); Minimize light exposure |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 16, 2026