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iFluor® 546 Anti-human CD11a Antibody
TS-1/22.1.1.13
TS-1/22.1.1.13 is an anti-human monoclonal antibody that targets the CD11a antigen. CD11a (also known as ITGAL or LFA-1α chain) is a 170 - 180 kD transmembrane glycoprotein that is found on the surface of cells such as NK cells, T cells, macrophages and B cells. CD11a plays a role in vital cellular pathways, namely, the integrin-mediated signaling pathway. Also, it has been closely linked to key biological processes like cell-cell adhesion, especially leukocyte cell-cell adhesion. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and CD18. CD11a is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD11a is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules, neuroinflammation and innate immunity. This antibody was purified through affinity chromatography and conjugated to iFluor® 546 (ex/em = 541/557 nm). It is compatible with the 532 nm laser and 575/25 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
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CatalogSize
Price
Quantity
10115080100 tests
Price
10115081500 tests
Price
 
Antibody properties

Other namesLFA-1A, Integrin aL, ITGAL
CloneTS-1/22.1.1.13
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.25
Correction factor (280 nm)0.15
Extinction coefficient (cm -1 M -1)
100000
1
Excitation (nm)541
Emission (nm)557
Quantum yield
0.67
1
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 21, 2026