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iFluor® 555 Anti-human CD4 Antibody
OKT-4
OKT-4 is an anti-human monoclonal antibody that targets the CD4 antigen. CD4 (also known as T4) is a 55 kD member of the Ig superfamily that is located on the surface of cells such as macrophages. In certain organisms, CD4 positively regulates kinase activity, promotes I-kappaB kinase/NF-kappaB signaling and upregulates transcription, DNA-templated. Additionally, it has been thought to be involved with essential biological processes such as immune response, especially adaptive immune response. CD4 is a member of critical cellular pathways, for instance, the cytokine-mediated signaling pathway, enzyme linked receptor protein signaling pathway and interleukin-15-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like Lck and IL-16. CD4 is a very popular antibody target, with over 185000 publications in the last decade. CD4 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 555 (ex/em = 557/570 nm). It is compatible with the 561 nm laser and 585/29 nm bandpass filter (for example, as in the BD FACSJazz™).
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CatalogSize
Price
Quantity
10043090100 tests
Price
10043091500 tests
Price
 
Antibody properties

Other namesLeu-3, T4
CloneOKT-4
HostMouse
IsotypeIgG2b, kappa
ReactivityHuman
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.23
Correction factor (280 nm)0.14
Extinction coefficient (cm -1 M -1)
100000
1
Excitation (nm)557
Emission (nm)570
Quantum yield
0.64
1
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 2, 2026