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iFluor® 647 Anti-human CD11a Antibody
HI111
HI111 is an anti-human monoclonal antibody that forms an immune complex with the CD11a antigen. CD11a (also known as Integrin alpha-L or LFA-1α chain) is a 170 - 180 kD transmembrane protein that is expressed on the surface of cells such as granulocytes and macrophages. CD11a has been associated with critical biological processes like cell-cell adhesion, especially leukocyte cell-cell adhesion. Moreover, it is a member of essential cellular pathways, for instance, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as CD18 and ICAM-1, 2, 3 and 4. CD11a is a fairly uncommon antibody target, with a little more than 3700 publications in the last decade. Even still, CD11a has a variety of applications in neuroscience and innate immunity research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 647 (ex/em = 656/670 nm). It is compatible with the 640 nm laser and 675/25 nm bandpass filter (for example, as in the BD Accuri™ C6 Plus).
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CatalogSize
Price
Quantity
101100F0100 tests
Price
101100F1500 tests
Price
 
Antibody properties

Other namesLFA-1A, Integrin aL, ITGAL
CloneHI111
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.03
Correction factor (280 nm)0.03
Correction factor (656 nm)0.0793
Extinction coefficient (cm -1 M -1)
250000
1
Excitation (nm)656
Emission (nm)670
Quantum yield
0.25
1
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 21, 2026