iFluor® 647 Anti-human CD36 Antibody *CB38*

The CB38 monoclonal antibody binds to human CD36, a 85 - 113 kD glycoprotein often expressed on the surface of epithelial cells, platelets, monocytes, endothelial cells and dendritic cells. CD36 has been thought to be involved with important biological processes such as intestinal absorption, especially intestinal cholesterol absorption. Furthermore, in certain organisms, it acts to positively regulate reactive oxygen species biosynthetic process, promotes cold-induced thermogenesis and plays a role in the upregulation of macrophage cytokine production. CD36 is a component of key cellular pathways, for example, the regulation of lipopolysaccharide-mediated signaling pathway, toll-like receptor signaling pathway and cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like IV and V and collagen I. CD36 is a moderately popular antibody target, with over 16000 publications in the last decade. CD36 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of cell biology, immunology and innate immunity. This antibody was purified through affinity chromatography and conjugated to iFluor® 647 (ex/em = 656/670 nm). It is compatible with the 640 nm laser and 660/20 nm bandpass filter (for example, as in the BD FACSAria™ II).

Page updated on September 2, 2025