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iFluor® 670 Anti-human CD19 Antibody
4G7
The 4G7 monoclonal antibody binds with human CD19, a 95 kD transmembrane protein commonly expressed on the surface of B cells and lymphocytes. CD19 plays a role in essential cellular pathways, for example, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. Moreover, in some organisms, it acts to positively regulate phosphatidylinositol 3-kinase activity, is an enhancer of protein kinase B signaling and is involved in the positive regulation of release of sequestered calcium ion into cytosol. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as Fyn and PI3-kinase. CD19 is a very popular antibody target, with over 30000 publications in the last decade. CD19 is essential for immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 670 (ex/em = 671/682 nm). It is compatible with the 642 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).
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product image
CatalogSize
Price
Quantity
101930H0100 tests
Price
101930H1500 tests
Price
 
Antibody properties

Other namesB4
Clone4G7
Hostmouse
Isotypemouse igg1
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.03
Correction factor (280 nm)0.033
Extinction coefficient (cm -1 M -1)
200000
1
Excitation (nm)671
Emission (nm)682
Quantum yield
0.55
1
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on October 16, 2025