iFluor® 670 Anti-human CD41 Antibody *HIP2*

The HIP2 monoclonal antibody binds to human CD41, a 22 kD glycoprotein frequently expressed on the surface of megakaryocytes and platelets. In certain organisms, CD41 is a promoter of leukocyte migration. Also, it acts in important cellular pathways, for example, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as von Willebrand factor (vWF), Fibrinogen and Fibronectin. CD41 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD41 is vital to cell adhesion, immunology and cell biology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 670 (ex/em = 671/682 nm). It is compatible with the 642 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).

Page updated on September 19, 2024