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iFluor® 680 Anti-human CD300a Antibody *MEM-260*

MEM-260 is an anti-human monoclonal antibody that is specific for the CD300a antigen. CD300a (alternatively called CLM-8) is a transmembrane protein that is expressed on the surface of cells such as macrophages, T cells, dendritic cells and B cells. In some organisms, CD300a is a repressor of MyD88-dependent toll-like receptor signaling pathway, suppresses B cell receptor signaling pathway and is a promoter of phosphoprotein phosphatase activity. Also, it is a member of important cellular pathways, for example, the negative regulation of B cell receptor signaling pathway, negative regulation of MyD88-dependent toll-like receptor signaling pathway and regulation of T cell receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like unknown. CD300a is a relatively rare antibody target, with fewer than 400 publications in the last decade. Even still, CD300a is essential for innate immunity and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 680 (ex/em = 684/701 nm).

Spectrum

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd300a antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 28, 2024

Ordering information

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Additional ordering information

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Antibody properties

Other namesCLM-8; IRp60; CMRF-35H
CloneMEM-260
Hostmouse
IsotypeMouse IgG1
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging

Spectral properties

Correction Factor (260 nm)

0.097

Correction Factor (280 nm)

0.094

Extinction coefficient (cm -1 M -1)

2200001

Excitation (nm)

684

Emission (nm)

701

Quantum yield

0.231

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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