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iFluor® 680 Anti-mouse/human/rat CD47 Antibody
MIAP410
The MIAP410 monoclonal antibody binds with mouse/human/rat CD47, a 42 - 52 kD transmembrane protein frequently located on the surface of b cells, thymocytes and epithelial cells. In many organisms, CD47 acts to positively regulate phagocytosis, is a promoter of cell population proliferation and enhances T cell activation. Also, it is involved with vital cellular pathways, for instance, the negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis and integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like Thrombospondin, SIRP and CD61. CD47 is a fairly uncommon antibody target, with a little more than 5000 publications in the last decade. Even still, CD47 has a variety of applications in immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 680 (ex/em = 684/701 nm).
product image
CatalogSize
Price
Quantity
104730I0100 tests
Price
104730I1500 tests
Price
 
Antibody properties

Other namesgp42, IAP, neurophilin, MER6, Integrin associated protein
CloneMIAP410
HostMouse
IsotypeIgG1, kappa
ReactivityMouse, Human, Rat
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.097
Correction factor (280 nm)0.094
Extinction coefficient (cm -1 M -1)
220000
1
Excitation (nm)684
Emission (nm)701
Quantum yield
0.23
1
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 21, 2026