iFluor® 710 Anti-human CD324 Antibody *67A4*

67A4 is an anti-human monoclonal antibody that targets the CD324 antigen. CD324 (also known as E-Cadherin) is a 100 kD member of the cadrin superfamily that is found on the surface of cells like erythrocytes. In certain organisms, CD324 is involved in the positive regulation of transcription, DNA-templated, enhances protein import into nucleus and negatively regulates cell migration. Also, it has been thought to be involved with key biological processes such as cell-cell adhesion, specifically cell-cell adhesion mediated by cadherin. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands. CD324 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD324 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of cell biology. This antibody was purified through affinity chromatography and conjugated to iFluor® 710 (ex/em = 717/739 nm).

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