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mFluor™ Red 780 Anti-human CD11b Antibody
ICRF44
ICRF44 is an anti-human monoclonal antibody that forms an immune complex with the CD11b antigen. CD11b (also known as Mo1 or Mac-1) is a 165 - 170 kD transmembrane glycoprotein that is expressed on the surface of cells such as dendritic cells, macrophages, NK cells and T cells. In some organisms, CD11b is involved in the positive regulation of neuron death, is a promoter of hippocampal neuron apoptotic process and is a positive regulator of protein targeting to membrane. Furthermore, it has been thought to be involved with vital biological processes such as cell adhesion, specifically cell-cell adhesion via plasma-membrane adhesion molecules. CD11b is a member of vital cellular pathways, for example, the integrin-mediated signaling pathway, apoptotic signaling pathway and toll-like receptor 4 signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like iC3b, ICAM-1, Factor X and 2. CD11b is a very popular antibody target, with over 45000 publications in the last decade. CD11b is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and immunology. This antibody was purified through affinity chromatography and conjugated to mFluor™ Red 780 (ex/em = 629/767 nm). It is compatible with the 633 nm laser and 783/56 nm bandpass filter (for example, as in the BD FACSVerse™).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 101120W0 | 100 tests | Price | |
| 101120W1 | 500 tests | Price |
Antibody properties
| Other names | CR3, Mac-1, Mo1, ITGAM, Integrin alpha-M |
| Clone | ICRF44 |
| Host | Mouse |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Absorbance (nm) | 630 |
| Correction factor (260 nm) | 0.101 |
| Correction factor (280 nm) | 0.116 |
| Extinction coefficient (cm -1 M -1) | 90000 1 |
| Excitation (nm) | 629 |
| Emission (nm) | 767 |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 2, 2026