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mFluor™ Violet 450 Anti-human CD123 Antibody
12H7
The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells. CD123 acts in vital cellular pathways, for instance, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like CD131. CD123 is a fairly uncommon antibody target, with a little more than 3900 publications in the last decade. Even still, CD123 is essential for immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Violet 450 (ex/em = 406/445 nm). It is compatible with the 405 nm laser and 450/50 nm bandpass filter (for example, as in the BD FACSCanto™).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 112310Z0 | 100 tests | Price | |
| 112310Z1 | 500 tests | Price |
Antibody properties
| Other names | IL-3Rα |
| Clone | 12H7 |
| Host | Mouse |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Absorbance (nm) | 406 |
| Correction factor (260 nm) | 0.338 |
| Correction factor (280 nm) | 0.078 |
| Extinction coefficient (cm -1 M -1) | 35000 1 |
| Excitation (nm) | 406 |
| Emission (nm) | 445 |
| Quantum yield | 0.81 1 |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 20, 2026