mFluor™ Violet 510 Anti-human CD279 Antibody *2E7*

2E7 is an anti-human monoclonal antibody that targets the CD279 antigen. CD279 (sometimes referred to as Programmed Death-1 or PD-1) is a 50 - 55 kD glycoprotein that is found on the surface of cells like B cells and T cells. CD279 is associated with a variety of biologically interesting macromolecules/ligands, namely, PDL1. CD279 is a relatively rare antibody target, with less than 1000 publications in the last decade. Even still, CD279 has been widely used in cancer biomarkers, immunology and inhibitory molecules research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Violet 510 (ex/em = 412/505 nm). It is compatible with the 405 nm laser and 525/50 nm bandpass filter (for example, as in the BD FACSCanto™).