mFluor™ Yellow 630 Anti-human CD117 Antibody *104D2*

mFluor™ Yellow 630 Anti-human CD117 Antibody

104D2

The 104D2 monoclonal antibody reacts with human CD117, a 145 kD single-pass type i membrane protein typically found on the surface of leukemias, embryonic stem cells, mesenchymal stem cells and mast cells. CD117 has been closely linked to vital biological processes like germ cell migration, specifically ectopic germ cell programmed cell death. In addition, in some organisms, it acts to positively regulate pseudopodium assembly, plays a role in the upregulation of long-term neuronal synaptic plasticity and is an inhibitor of programmed cell death. CD117 is a component of critical cellular pathways, for example, the transmembrane receptor protein tyrosine kinase signaling pathway, Kit signaling pathway and Fc receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as MGF, SCF and KL. CD117 is a moderately popular antibody target, with over 11000 publications in the last decade. CD117 has been widely used in stem cells and immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Yellow 630 (ex/em = 610/627 nm). It is compatible with the 628 nm laser and 670/30 nm bandpass filter (for example, as in the BD FACSymphony™ A5).

Protocol

SDS

COA

Catalog	Size	Price	Quantity
11170130	100 tests	Price
11170131	500 tests	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of cd117 antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Other names	c-kit, SCFR
Clone	104D2
Host	Mouse
Isotype	Mouse IgG1
Reactivity	Human
Application	Flow Cytometry (FACS), Fluorescence Imaging

Spectral properties

Absorbance (nm)	561
Extinction coefficient (cm ^-1 M ^-1)	110000 ¹
Excitation (nm)	570
Emission (nm)	632

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on August 5, 2024