Name: N6-Methyladenosine-Biotin conjugate
Brand: AAT Bioquest
SKU: 17100
Price: 348 USD
Availability: InStock

N6-Methyladenosine-Biotin conjugate

N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast. It is also found in tRNA, rRNA, and small nuclear RNA (snRNA) as well as several long non-coding RNA, such as Xist. The methylation of adenosine is directed by a large N6-Methyladenosine methyltransferase complex containing METTL3 as the SAM-binding sub-unit. The biological functions of m6A are mediated through a group of RNA binding proteins that specifically recognize the methylated adenosine on RNA. This biotinylated N6-Methyladenosine derivative can be used for detecting the RNA modifications related to N6-Methyladenosine.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
17100	1 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of N6-Methyladenosine-Biotin conjugate to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	132.649 µL	663.244 µL	1.326 mL	6.632 mL	13.265 mL
5 mM	26.53 µL	132.649 µL	265.298 µL	1.326 mL	2.653 mL
10 mM	13.265 µL	66.324 µL	132.649 µL	663.244 µL	1.326 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	753.87 g/mol	=	mL	x	mM	=	mmol

Citations

View all 28 citations: Citation Explorer

HIV-1 envelope proteins up-regulate N (6)-methyladenosine levels of cellular RNA independently of viral replication

Authors:

Tirumuru, N., Wu, L.

Journal:

J Biol Chem (2019): 3249-3260

Changes of RNA N(6)-methyladenosine in the hormesis effect induced by arsenite on human keratinocyte cells

Authors:

Chen, H., Zhao, T., Sun, D., Wu, M., Zhang, Z.

Journal:

Toxicol In Vitro (2019): 84-92

N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1alpha signalling axis

Authors:

Zhuang, C., Zhuang, C., Luo, X., Huang, X., Yao, L., Li, J., Li, Y., Xiong, T., Ye, J., Zhang, F., Gui, Y.

Journal:

J Cell Mol Med (2019): 2163-2173

A dynamic reversible RNA N(6) -methyladenosine modification: current status and perspectives

Authors:

Bi, Z., Liu, Y., Zhao, Y., Yao, Y., Wu, R., Liu, Q., Wang, Y., Wang, X.

Journal:

J Cell Physiol (2019): 7948-7956

Transcriptome-wide analysis of N6-methyladenosine uncovers its regulatory role in gene expression in the lepidopteran Bombyx mori

Authors:

Li, B., Wang, X., Li, Z., Lu, C., Zhang, Q., Chang, L., Li, W., Cheng, T., Xia, Q., Zhao, P.

Journal:

Insect Mol Biol (2019): se name="17100.enl" path="C:\Users\aatbi\Drop

Physical properties

Molecular weight	753.87
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H340
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	41116134

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Page updated on October 13, 2025