Actively helping customers, employees and the global community during the coronavirus SARS-CoV-2 outbreak.  Learn more >>

N6-Methyladenosine-Biotin conjugate

Chemical structure for N6-Methyladenosine-Biotin conjugate.
Chemical structure for N6-Methyladenosine-Biotin conjugate.
Ordering information
Price ()
Catalog Number17100
Unit Size
Find Distributor
Additional ordering information
Telephone1-408-733-1055
Fax1-408-733-1304
Emailsales@aatbio.com
InternationalSee distributors
ShippingStandard overnight for United States, inquire for international
Physical properties
Molecular weight753.87
SolventDMSO
Storage, safety and handling
H-phraseH303, H313, H340
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC41116134
Related products
Biotin *CAS 58-85-5*
Biotin, succinimidyl ester *CAS 35013-72-0*
Biotin ethylenediamine *CAS 1217450-40-2*
Biotin cadaverine
Biotin C2 maleimide
Biotin-4-fluorescein *CAS 1032732-74-3*
Biotin hydrazide *CAS 66640-86-6*
Biotin-X NTA [Biotin-X nitrilotriacetic acid, potassium salt] *CAS 856661-92-2*
Biotin-X, succinimidyl ester *CAS 72040-63-2*
Biotin PEG2 amine *CAS 138529-46-1*
Biotin PEG2 maleimide *CAS 305372-39-8*
Biotin PEG2 succinimidyl ester
Biotin-PEG3-azide *CAS 945633-30-7*
Biotin Azide
Biotin Alkyne *CAS 773888-45-2*
Biotin PEG4 succinimidyl ester
ReadiView™ biotin acid
ReadiView™ biotin amine
ReadiView™ biotin hydrazide
ReadiView™ biotin maleimide
ReadiView™ biotin succinimidyl ester
ReadiLink™ Protein Biotinylation Kit *Powered by ReadiView™ Biotin Visionization Technology*
Amplite® Colorimetric Biotin Quantitation Kit
Biotin-11-dUTP *1 mM in Tris Buffer (pH 7.5)* *CAS 86303-25-5*
Biotin-16-dUTP *1 mM in Tris Buffer (pH 7.5)* *CAS 136632-31-0*
Biotin-20-dUTP *1 mM in Tris Buffer (pH 7.5)*
Cal-520®-Biotin Conjugate
Phalloidin-Biotin Conjugate
FMOC-Lys(Biotin)-OH
Biotin-14-dCTP *1 mM in Tris Buffer (pH 7.5)*
Biotin PEG3 amine
Annexin V-Biotin conjugate
Biotin Styramide *Superior Replacement for Biotin Tyramide*
Cy5 biotin conjugate
Biotin-cAMP conjugate
2',3'-cGAMP-Biotin conjugate
Cy5.5 biotin conjugate
Biotin-PEG4-tyramide
HRP-Biotin Conjugate
Biotin-11-dATP
Biotin-11-dGTP *1 mM in Tris Buffer (pH 7.5)*
Biotin NTA
Biotin-X IDA
ReadiCleave™ SSL biotin NHS ester
Biotin-dT Phosphoramidite
ReadiLink™ Biotin Nick Translation dsDNA Labeling Kit
ReadiLink™ Biotin Oligo and ssDNA Labeling Kit
AF532 PEG4 biotin conjugate
Biotin PEG 4 Alkyne
Cy3 biotin conjugate
Cy7 biotin conjugate
Biotin C2 Azide
mFluor™ UV 375 Biotin Conjugate
mFluor™ UV 460 Biotin Conjugate
mFluor™ Violet 500 Biotin Conjugate
mFluor™ Violet 540 Biotin Conjugate
mFluor™ Red 780 Biotin Conjugate
Biotin Phosphoramidite
Show More (58)

OverviewpdfSDSpdfProtocol


Molecular weight
753.87
N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast. It is also found in tRNA, rRNA, and small nuclear RNA (snRNA) as well as several long non-coding RNA, such as Xist. The methylation of adenosine is directed by a large N6-Methyladenosine methyltransferase complex containing METTL3 as the SAM-binding sub-unit. The biological functions of m6A are mediated through a group of RNA binding proteins that specifically recognize the methylated adenosine on RNA. This biotinylated N6-Methyladenosine derivative can be used for detecting the RNA modifications related to N6-Methyladenosine.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of N6-Methyladenosine-Biotin conjugate to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM132.649 µL663.244 µL1.326 mL6.632 mL13.265 mL
5 mM26.53 µL132.649 µL265.298 µL1.326 mL2.653 mL
10 mM13.265 µL66.324 µL132.649 µL663.244 µL1.326 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)Molecular weightVolume (Calculate)Concentration (Calculate)Moles
/=x=

Citations


View all 28 citations: Citation Explorer
Changes of RNA N(6)-methyladenosine in the hormesis effect induced by arsenite on human keratinocyte cells
Authors: Chen, H., Zhao, T., Sun, D., Wu, M., Zhang, Z.
Journal: Toxicol In Vitro (2019): 84-92
N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1alpha signalling axis
Authors: Zhuang, C., Zhuang, C., Luo, X., Huang, X., Yao, L., Li, J., Li, Y., Xiong, T., Ye, J., Zhang, F., Gui, Y.
Journal: J Cell Mol Med (2019): 2163-2173
A dynamic reversible RNA N(6) -methyladenosine modification: current status and perspectives
Authors: Bi, Z., Liu, Y., Zhao, Y., Yao, Y., Wu, R., Liu, Q., Wang, Y., Wang, X.
Journal: J Cell Physiol (2019): 7948-7956
Transcriptome-wide analysis of N6-methyladenosine uncovers its regulatory role in gene expression in the lepidopteran Bombyx mori
Authors: Li, B., Wang, X., Li, Z., Lu, C., Zhang, Q., Chang, L., Li, W., Cheng, T., Xia, Q., Zhao, P.
Journal: Insect Mol Biol (2019): se name="17100.enl" path="C:\Users\aatbi\Drop
RNA N6-methyladenosine modification participates in miR-660/E2F3 axis-mediated inhibition of cell proliferation in gastric cancer
Authors: He, X., Shu, Y.
Journal: Pathol Res Pract (2019): se name="17100.enl" path="C:\Users\aatbi\Drop
Importance of m N(6)-methyladenosine (m(6)A) RNA modification in cancer
Authors: Tuncel, G., Kalkan, R.
Journal: Med Oncol (2019): 36
The role of N(6)-methyladenosine RNA methylation in the heat stress response of sheep (Ovis aries)
Authors: Lu, Z., Ma, Y., Li, Q., Liu, E., Jin, M., Zhang, L., Wei, C.
Journal: Cell Stress Chaperones (2019): 333-342
Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats
Authors: Fu, Y., Zorman, B., Sumazin, P., Sanna, P. P., Repunte-Canonigo, V.
Journal: PLoS One (2019): e0203566
Identifying N(6)-methyladenosine sites using extreme gradient boosting system optimized by particle swarm optimizer
Authors: Zhao, X., Zhang, Y., Ning, Q., Zhang, H., Ji, J., Yin, M.
Journal: J Theor Biol (2019): 39-47
N1-Methyladenosine detection with CRISPR-Cas13a/C2c2
Authors: Chen, Y., Yang, S., Peng, S., Li, W., Wu, F., Yao, Q., Wang, F., Weng, X., Zhou, X.
Journal: Chem Sci (2019): 2975-2979