PacBlue Anti-human CD111 Antibody *R1.302*

R1.302 is an anti-human monoclonal antibody that forms an immune complex with the CD111 antigen. CD111 (also known as PVRL1 or Nectin-1) is a 75 kD single-pass type I membrane protein that is found on the surface of cells like erythrocytes, endothelial cells, epithelial cells, stem cells and macrophages. CD111 has been thought to be involved with critical biological processes like cell-cell adhesion, particularly homophilic cell adhesion via plasma membrane adhesion molecules, and is associated with a variety of biologically interesting macromolecules/ligands, for instance, nectin3 and afadin gd. CD111 is a relatively rare antibody target, with fewer than 90 publications in the last decade. Even still, CD111 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of neuroscience. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 448/45 nm bandpass filter (for example, as in the BD FACSVerse™).

Page updated on September 19, 2024