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PacBlue Anti-human CD11a Antibody
R7-1
R7-1 is an anti-human monoclonal antibody that forms an immune complex with the CD11a antigen. CD11a (alternatively called αL Integrin or Integrin alpha-L) is a 170 - 180 kD transmembrane glycoprotein that is found on the surface of cells like T cells, NK cells, macrophages, granulocytes and B cells. CD11a has been closely linked to critical biological processes like cell-cell adhesion, particularly leukocyte cell-cell adhesion. In addition, it is involved with key cellular pathways, in particular, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1, 2, 3 and 4 and CD18. CD11a is a fairly uncommon antibody target, with a little more than 3700 publications in the last decade. Even still, CD11a is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of cell adhesion and immunology. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 450/50 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant X).
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CatalogSize
Price
Quantity
101141K0100 tests
Price
101141K1500 tests
Price
 
Antibody properties

Other namesLFA-1A; Integrin aL; ITGAL
CloneR7-1
Hostmouse
Isotypemouse igg1
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.15
Correction factor (280 nm)0.2
Extinction coefficient (cm -1 M -1)
46000
Excitation (nm)404
Emission (nm)455
Quantum yield
0.78
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on September 25, 2025