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PacBlue Anti-human CD300a Antibody
MEM-260
MEM-260 is an anti-human monoclonal antibody that is specific for the CD300a antigen. CD300a (alternatively called CLM-8) is a transmembrane protein that is expressed on the surface of cells such as macrophages, T cells, dendritic cells and B cells. In some organisms, CD300a is a repressor of MyD88-dependent toll-like receptor signaling pathway, suppresses B cell receptor signaling pathway and is a promoter of phosphoprotein phosphatase activity. Also, it is a member of important cellular pathways, for example, the negative regulation of B cell receptor signaling pathway, negative regulation of MyD88-dependent toll-like receptor signaling pathway and regulation of T cell receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like unknown. CD300a is a relatively rare antibody target, with fewer than 400 publications in the last decade. Even still, CD300a is essential for innate immunity and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 450/50 nm bandpass filter (for example, as in the BD FACSAria™ III).
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CatalogSize
Price
Quantity
130001I0100 tests
Price
130001I1500 tests
Price
 
Antibody properties

Other namesCLM-8, IRp60, CMRF-35H
CloneMEM-260
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.15
Correction factor (280 nm)0.2
Extinction coefficient (cm -1 M -1)
46000
Excitation (nm)404
Emission (nm)455
Quantum yield
0.78
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 16, 2026