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PacBlue Anti-human CD34 Antibody *4H11*

4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen. CD34 (sometimes called Gp105-120) is a 105 - 120 kD glycoprotein that is located on the surface of cells like endothelial cells and stem cells. In many organisms, CD34 plays a role in the downregulation of tumor necrosis factor production, positively regulates granulocyte colony-stimulating factor production and is involved in the positive regulation of vasculogenesis. Also, it has been associated with vital biological processes such as endothelium development, especially glomerular endothelium development. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like MadCAM-1, CRKL and L-Selectin. CD34 is a very popular antibody target, with over 55000 publications in the last decade. CD34 is vital to neuroscience, neuroinflammation and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 450/50 nm bandpass filter (for example, as in the BD FACSymphony™ A5).

Spectrum

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd34 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on September 18, 2024

Ordering information

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Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Antibody properties

Other namesGp105-120
Clone4H11
Hostmouse
Isotypemouse IgG1
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging

Spectral properties

Correction Factor (260 nm)

0.15

Correction Factor (280 nm)

0.2

Extinction coefficient (cm -1 M -1)

46000

Excitation (nm)

404

Emission (nm)

455

Quantum yield

0.78

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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