PacBlue Anti-human CD41 Antibody HIP8

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Additional ordering information

Telephone	1-800-990-8053
Fax	1-800-609-2943
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Shipping	Standard overnight for United States, inquire for international

Spectral properties

Correction Factor (260 nm)	0.15
Correction Factor (280 nm)	0.2
Extinction coefficient (cm ^-1 M ^-1)	46000
Excitation (nm)	404
Emission (nm)	455
Quantum yield	0.78

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22

Overview SDS Protocol

Other names

GPIIb; ITGA2B

Clone

HIP8

Host

mouse

Isotype

mouse IgG1

Reactivity

human

Application

Flow Cytometry (FACS); Fluorescence Imaging

Correction Factor (260 nm)

0.15

Correction Factor (280 nm)

0.2

Extinction coefficient (cm ^-1 M ^-1)

46000

Excitation (nm)

404

Emission (nm)

455

Quantum yield

0.78

HIP8 is an anti-human monoclonal antibody that recognizes the CD41 antigen. CD41 (also known as GP2B) is a 22 kD member of the Integrin family that is found on the surface of cells such as stem cells. CD41 is a component of critical cellular pathways, for instance, the integrin-mediated signaling pathway. Moreover, in some organisms, it enhances leukocyte migration. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as von Willebrand factor (vWF) and Fibrinogen. CD41 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD41 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell biology and cell adhesion. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 448/45 nm bandpass filter (for example, as in the BD FACSVerse™).

Spectrum

Open in Advanced Spectrum Viewer

Spectral properties

Correction Factor (260 nm)	0.15
Correction Factor (280 nm)	0.2
Extinction coefficient (cm ^-1 M ^-1)	46000
Excitation (nm)	404
Emission (nm)	455
Quantum yield	0.78

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Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd41 antibody with HRP). A list of available labels can be found in the table below:

AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780