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PacBlue Anti-non-human primates/ human CD49b Antibody
AK7
The AK7 monoclonal antibody reacts with non-human primates/ human CD49b, a 170 kD member of the Integrin alpha chain family commonly located on the surface of activated T cells, B cells and monocytes. In some organisms, CD49b plays a role in the upregulation of alkaline phosphatase activity, is involved in the positive regulation of translation and is a promoter of epithelial cell migration. Additionally, it plays a role in essential cellular pathways, for example, the integrin-mediated signaling pathway and collagen-activated signaling pathway. CD49b has been associated with critical biological processes such as cell adhesion, specifically cell adhesion mediated by integrin, and is associated with a variety of biologically interesting macromolecules/ligands, for example, laminin, collagen and MMP-1. CD49b is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD49b is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 450/50 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 104911K0 | 100 tests | Price | |
| 104911K1 | 500 tests | Price |
Antibody properties
| Other names | Integrin alpha-2, VLA-2 subunit alpha, ITGA2, α2 integrin, VLA-2 α chain, Integrin α2 chain |
| Clone | AK7 |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Non-Human Primates, Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.15 |
| Correction factor (280 nm) | 0.2 |
| Extinction coefficient (cm -1 M -1) | 46000 |
| Excitation (nm) | 404 |
| Emission (nm) | 455 |
| Quantum yield | 0.78 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 3, 2026